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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAN3 All Species: 25.45
Human Site: S208 Identified Species: 37.33
UniProt: Q58A45 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q58A45 NP_787050.4 741 82181 S208 P K I T P H T S P A P R R R S
Chimpanzee Pan troglodytes XP_001136622 741 82148 S208 P K I T P H T S P A P R R R S
Rhesus Macaque Macaca mulatta XP_001097210 741 82134 S208 P K I T P H T S P A P R R R S
Dog Lupus familis XP_543150 987 105833 S454 P K I T P H T S P A P R R R S
Cat Felis silvestris
Mouse Mus musculus Q640Q5 691 76362 K195 S S G Q V I Q K E T V G G T T
Rat Rattus norvegicus XP_002724835 883 95283 S350 P K I T P H T S P A P R R R S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519591 717 78728 N212 S A S T P V N N P V T Q A P S
Chicken Gallus gallus XP_417120 757 83269 S225 P K I T P H T S P A P R R R S
Frog Xenopus laevis NP_001128699 631 68072 Y135 G S P G E A N Y P R M Q Q R M
Zebra Danio Brachydanio rerio XP_002666687 799 86684 T267 P L H S P K I T P H T S P A P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_728797 788 85176 M212 A A P F V S S M S A Q T P L K
Honey Bee Apis mellifera XP_623553 607 67474 E111 V G T E D G T E T I G N V G A
Nematode Worm Caenorhab. elegans P34653 632 71182 Q136 Q S A Y D R Y Q L E N R G G T
Sea Urchin Strong. purpuratus XP_796055 760 83393 P227 L H S P G G S P N T S R K E F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36102 679 76436 G183 P S I A N S G G I N I N A T D
Red Bread Mold Neurospora crassa Q7SDP4 656 73993 F160 G G L Y S D P F S I S S L G Q
Conservation
Percent
Protein Identity: 100 99.8 99.7 74.4 N.A. 90.1 82.2 N.A. 80.8 78.3 58.4 68.2 N.A. 38.5 41.8 31.9 49.3
Protein Similarity: 100 100 99.8 74.7 N.A. 90.9 83 N.A. 86 84.1 64 75 N.A. 55.7 59.6 49.5 62.6
P-Site Identity: 100 100 100 100 N.A. 0 100 N.A. 26.6 100 13.3 20 N.A. 6.6 6.6 6.6 6.6
P-Site Similarity: 100 100 100 100 N.A. 6.6 100 N.A. 40 100 26.6 33.3 N.A. 13.3 13.3 13.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21.7 28
Protein Similarity: N.A. N.A. N.A. N.A. 42.1 45.2
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 0
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 13 7 7 0 7 0 0 0 44 0 0 13 7 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 13 7 0 0 0 0 0 0 0 0 7 % D
% Glu: 0 0 0 7 7 0 0 7 7 7 0 0 0 7 0 % E
% Phe: 0 0 0 7 0 0 0 7 0 0 0 0 0 0 7 % F
% Gly: 13 13 7 7 7 13 7 7 0 0 7 7 13 19 0 % G
% His: 0 7 7 0 0 38 0 0 0 7 0 0 0 0 0 % H
% Ile: 0 0 44 0 0 7 7 0 7 13 7 0 0 0 0 % I
% Lys: 0 38 0 0 0 7 0 7 0 0 0 0 7 0 7 % K
% Leu: 7 7 7 0 0 0 0 0 7 0 0 0 7 7 0 % L
% Met: 0 0 0 0 0 0 0 7 0 0 7 0 0 0 7 % M
% Asn: 0 0 0 0 7 0 13 7 7 7 7 13 0 0 0 % N
% Pro: 50 0 13 7 50 0 7 7 57 0 38 0 13 7 7 % P
% Gln: 7 0 0 7 0 0 7 7 0 0 7 13 7 0 7 % Q
% Arg: 0 0 0 0 0 7 0 0 0 7 0 50 38 44 0 % R
% Ser: 13 25 13 7 7 13 13 38 13 0 13 13 0 0 44 % S
% Thr: 0 0 7 44 0 0 44 7 7 13 13 7 0 13 13 % T
% Val: 7 0 0 0 13 7 0 0 0 7 7 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 13 0 0 7 7 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _